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MMDB Description
55056Protein Tyrosine Phosphatase 1B Cysteinyl-phosphate Intermediate
55117Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Two Bis(para-phosphophenyl)methane (Bppm) Molecules
12010Human Ptp1b Catalytic Domain Complexed With TPI
73484Cyclic Peptide Inhibitor of Human Ptp1b
12186Human Ptp1b Complexed With Tpicooh
13095Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 6-(oxalyl-amino)-1h-indole-5-carboxylic Acid
13096Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 3-(oxalyl-amino)-naphthalene-2-carboxlic Acid
13097Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 2-(oxalyl-amino)-benzoic Acid
13098Crystal Structure of Protein Tyrosine Phosphatase 1B (R47v, D48n) Complexed With 2-(oxalyl-amino-4,7-dihydro-5h- Thieno[2,3-c]pyran-3-carboxylic Acid
13099Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 2-(oxalyl-amino-4,7-dihydro-5h-thieno[2,3- C]pyran-3-carboxylic Acid
13100Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 2-(oxalyl-amino)-4,5,6,7-tetrahydro- Thieno[2,3-c]pyridine-3-carboxylic Acid
13004Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With 5-iodo-2-(oxalyl-amino)-benzoic Acid
15270Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Acetyl-d-a-d-bpa-ptyr-l-i-p-q-q-g
15271Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Acetyl-e-l-e-f-ptyr-m-d-y-e-nh2
15430Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With a Tri-phosphorylated Peptide (Rdi(ptr) Etd(ptr)(ptr)rk) From the Insulin Receptor Kinase
15431Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With a Mono-phosphorylated Peptide (Etdy(ptr) Rkggkgll) From the Insulin Receptor Kinase
15432Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With a Bis-phosphorylated Peptide (Etd(ptr)(ptr) Rkggkgll) From the Insulin Receptor Kinase
49208Human Ptp1b Catalytic Domain Complexed With Pnu177496
16391Human Ptp1b Catalytic Domain Complexes With Pnu179326
13559Residue 259 IS a KEY Determinant of Substrate Specificity of Protein-tyrosine Phosphatase 1B and Alpha
16806Crystal Structure of APO Human Ptp1b (C215s) Mutant
18814Human Ptp1b Catalytic Domain Complexed With Pnu177836
19841Human Tyrosine Phosphatase 1B Complexed With an Inhibitor
19843Human Tyrosine Phosphatase 1B Complexed With an Inhibitor
19603Crystal Structure of Ptp1b Complexed With 7-(1,1-dioxo-1h- Benzo[d]isothiazol-3-yloxymethyl)-2-(oxalyl-amino)-4,7- Dihydro-5h-thieno[2,3-c]pyran-3-carboxylic Acid
20258Structure of Ptp1b in Complex With a Peptidic Bisphosphonate Inhibitor
22691Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 12 Using a Linked-fragment Strategy
22696Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 23 Using a Linked-fragment Strategy
22698Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 5 Using a Linked-fragment Strategy
22740Ptp1b R47c Modified at C47 With N-[4-(2-{2-[3-(2-bromo- Acetylamino)-propionylamino]-3-hydroxy-propionylamino}- Ethyl)-phenyl]-oxalamic Acid
22448Crystal Structure of the Ptp1b Complexed With Sp7343-sp7964, a Ptyr Mimetic
23050Potent, Selective Inhibitors of Protein Tyrosine Phosphatase 1B Using a Second Phosphotyrosine Binding Site, Complexed With Compound 19
23526Ptp1b With the Catalytic Cysteine Oxidized to a Sulfenyl-amide Bond
23527Ptp1b With the Catalytic Cysteine Oxidized to Sulfonic Acid
23528Oxidation State of Protein Tyrosine Phosphatase 1B
50621Oxidation State of Protein Tyrosine Phosphatase 1B
23530Oxidation State of Protein Tyrosine Phosphatase 1B
23531Oxidation State of Protein Tyrosine Phosphatase 1B
23097Oxalyl-aryl-amino Benzoic Acid Inhibitors of Ptp1b, Compound 17
23098Oxalyl-aryl-amino Benzoic Acid Inhibitors of Ptp1b, Compound 8B
24256Crystal Structure of the C215d Mutant of Protein Tyrosine Phosphatase 1B
24335Non-carboxylic Acid-containing Inhibitor of Ptp1b Targeting the Second Phosphotyrosine Site
74183Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Phosphotyrosine-containing Tetra-peptide (Ac-depyl-nh2)
74184Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Phosphotyrosine-containing Hexa-peptide (Dadepyl-nh2)
50889Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Phosphotyrosine
57182Crystal Structure of Protein Tyrosine Phosphatase 1B Complexed With Two Phosphotyrosine Molecules
24170Crystal Structure of Protein Tyrosine Phosphatase 1B With Potent and Selective Bidentate Inhibitor Compound 2
24801Dual-site Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked Fragment Strategy and a Malonate Head on the First Site
24824a Highly Efficient Approach to a Selective and Cell Active Ptp1b Inhibitors
24845The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 2
24846The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 3
24847The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 4
24848The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 6
24849The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 9
24850The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 11
25112Monoacid-based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B
293811.95 a Structure of APO Protein Tyrosine Phosphatase 1B
28639Allosteric Inhibition of Protein Tyrosine Phosphatase 1B
28640Allosteric Inhibition of Protein Tyrosine Phosphatase 1B
28644Allosteric Inhibition of Protein Tyrosine Phosphatase 1B
31380Protein Tyrosine Phosphatase 1B With Active Site Inhibitor
30146Ptp1b Complexed With Isoxazole Carboxylic Acid
36125Crystal Structure of Ptp1b With Bicyclic Thiophene Inhibitor
36126Crystal Structure of Ptp1b With Tricyclic Thiophene Inhibitor
36139Crystal Structure of a Complex Between Ptp1b and the Insulin Receptor Tyrosine Kinase
33492Structure-based Design of Protein Tyrosine Phosphatase-1b Inhibitors
33493Structure-based Design of Protein Tyrosine Phosphatase-1b Inhibitors
40756Structure of Protein Tyrosine Phosphatase 1B (P212121)
40757Structure of Protein Tyrosine Phosphatase 1B (C2)
40758Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
40759Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
40760Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
40761Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
40762Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
41379Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein Tyrosine Phosphatase 1B
41380Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein Tyrosine Phosphatase 1B
41381Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein Tyrosine Phosphatase 1B
41382Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein Tyrosine Phosphatase 1B
41383Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein Tyrosine Phosphatase 1B
36533The Structure of the S295f Mutant of Human Ptp1b
36862Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36863Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36864Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36865Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36866Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36867Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
36868Protein Tyrosine Phosphatase 1B With Sulfamic Acid Inhibitors
37385The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 2
37386The Structure of Phosphotyrosine Phosphatase 1B in Complex With Compound 2
40973Crystal Structure of Ptp1b With Monocyclic Thiophene Inhibitor
40976Crystal Structure of Ptp1b With a Monocyclic Thiophene Inhibitor
41019Crystal Structure of Ptp1b With Monocyclic Thiophene Inhibitor
58040Crystal Structure of Human Protein Tyrosine Phosphatase 1B
58041Crystal Structure of Human Protein Tyrosine Phosphatase 1B
45830Crystal Structure of Ptp1b-inhibitor Complex
45831Crystal Structure of Ptp1b-inhibitor Complex
63072Crystal Structure of Ptp1b-inhibitor Complex
63073Crystal Structure of Ptp1b-inhibitor Complex
63074Crystal Structure of Ptp1b-inhibitor Complex
63075Crystal Structure of Ptp1b-inhibitor Complex
60634Crystal Structure of Protein Tyrosine Phosphatase 1B in Complex With an Isothiazolidinone-containing Inhibitor
60635Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With an Isothiazolidinone-containing Inhibitor
60636Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With an Isothiazolidinone-containing Inhibitor
60637Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With an Isothiazolidinone-containing Inhibitor
60638Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With an Isothiazolidinone-containing Inhibitor
67148Crystal Structure of Ptp1b-inhibitor Complex
67149Crystal Structures of Ptp1b-inhibitor Complexes
83945Crystal Structure of Protein-tyrosine Phosphatase 1B
83946Crystal Structure of Protein-tyrosine Phosphatase 1B
64889Ptp1b in Complex With a Phosphonic Acid Inhibitor
66910Crystal Structure Ptp1b Complex With Aryl Seleninic Acid
75129Crystal Structure Ptp1b Complex With Small Molecule Compound Lzp-6
75130Crystal Structure Ptp1b Complex With Small Molecule Inhibitor Lzp-25
67919Crystal Structure of the S-nitrosylated Cys215 of Ptp1b
80797Protein Tyrosine Phosphatase 1B - Transition State Analog FO First Catalytic Step
80798Protein Tyrosine Phosphatase 1B - Transition State Analog FO Second Catalytic Step